Mohammed Saleem

This study shows how neuronal lipid composition affects full-length tau assembly, mechanics, and membrane interactions, revealing distinct states of tau-membrane interaction based on lipid type and tau assembly state.

This study shows pathogenic bacteria use extracellular vesicles to alter host membrane mechanics, preventing phagosome maturation and aiding infection.

This study shows that mycobacterial load and direct contact determine phagosome fate by altering membrane mechanics, leading to spacious or compact phagosomal states that influence bacterial egress.

This study shows that lipid membrane interfaces drive α-synuclein condensation and fibrillation at low concentrations, revealing a mechanism for its propagation in neurodegeneration.

This study reveals how ESAT-6 disrupts the phagosomal membrane through fibril-mediated vesiculation, leading to host cell death and promoting Mtb infection.

This study investigates how bacterial extracellular vesicles interact with host lipid membranes, showing they increase membrane fluidity and preferentially bind to liquid-disordered regions.