Molecular BiologyACS Chemical BiologyPeer-reviewed
Identification of herboxidiene features that mediate conformation-dependent SF3B1 interactions to inhibit splicing.
Adriana Gamboa Lopez, Srinivasa Rao Allu, Patricia Mendez…·Melissa S. Jurica
The paper identifies features of herboxidiene that mediate conformation-dependent SF3B1 interactions and inhibit splicing by interacting with SF3B1 sidechains.