Author

Arun Kumar Ghosh

Purdue University West LafayetteORCID 0000-0003-2472-1841Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Melissa S. JuricaiD· 2 shared Adriana Gamboa Lopez· 1 shared Guddeti Chandrashekar Reddy· 1 shared Hannah M. Maul-NewbyiD· 1 shared Meredith SteversiD· 1 shared Patricia MendeziD· 1 shared Srinivasa Rao AlluiD· 1 shared Veronica K. Urabe· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 18 mutual co-author links

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2 shared papersMolecular Biology

Melissa S. JuricaORCID

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2 papers

Recent·Most cited

Molecular BiologyPLoS ONEPeer-reviewedOct 14, 2021

U2 snRNA structure is influenced by SF3A and SF3B proteins but not by SF3B inhibitors

Veronica K. Urabe, Meredith Stevers, Arun Kumar Ghosh, Melissa S. Jurica

The paper investigates how SF3A and SF3B proteins affect U2 snRNA structure and how SF3B inhibitors impact spliceosome assembly.

4 citations

experimental assay

𝕏 PostBluesky

Molecular BiologyACS Chemical BiologyPeer-reviewedFeb 22, 2021

Identification of herboxidiene features that mediate conformation-dependent SF3B1 interactions to inhibit splicing.

Adriana Gamboa Lopez, Srinivasa Rao Allu, Patricia Mendez…·Melissa S. Jurica

The paper identifies features of herboxidiene that mediate conformation-dependent SF3B1 interactions and inhibit splicing by interacting with SF3B1 sidechains.

14 citations

experimental assaydrug response / drug discovery

𝕏 PostBluesky