Author

Thomas Alexander Quinn

Dalhousie UniversityORCID 0000-0002-2437-5785Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:electrophysiology· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Peter Karl KohliD· 3 shared Joachim GreineriD· 2 shared Matthew R. StoyekiD· 2 shared Agata SulejiD· 1 shared Ahmed F. RamadaniD· 1 shared Albert DasíiD· 1 shared Behzad Taeb· 1 shared Breanne Ashleigh CameroniD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersPhysiology

Peter Karl KohlORCID

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3 papers

Recent·Most cited

Channelrhodopsin Ion Selectivity Determines Mechanisms and Efficacy of Optogenetic Defibrillation in Human Atria and Ventricles

Sophia Ohnemus, Albert Dasí, Ahmed F. Ramadan, Joachim Greiner, Eike M. Wülfers, Matthew R. Stoyek, Linda Tillert, Johannes Vierock, Thomas Alexander Quinn, Peter Karl Kohl, Patrick M. Boyle, Viviane Timmermann, Franziska Schneider‐Warme

This study compares the defibrillation efficacy of different channelrhodopsins in human cardiac tissue using simulations, finding that ion selectivity affects arrhythmia termination mechanisms and success.

The Journal of Physiology · Oct 17, 2026Peer-reviewedPhysiology

Disturbed repolarisation-relaxation coupling during acute ischaemia permits systolic mechano-arrhythmogenesis.

Breanne Ashleigh Cameron, Peter Baumeister, Tarek Lawen, Sara A. Rafferty, Behzad Taeb, Matthew R. Stoyek, Joachim Greiner, Ilija Uzelac, Flavio H. Fenton, Rémi Peyronnet, Peter Karl Kohl, Thomas Alexander Quinn

This study shows that disturbed repolarisation-relaxation coupling during acute ischaemia increases systolic mechano-arrhythmogenesis, which can be mitigated by restoring coupling or targeting calcium, TRPA1, or ROS.

Circulation Research · Jun 2, 2025Peer-reviewedPhysiology

Transcriptome profile of the zebrafish atrioventricular canal reveals molecular signatures of pacemaker and valve mesenchyme

Karim Abu Nahia, Maciej Migdał, Thomas Alexander Quinn, Kar‐Lai Poon, Maciej Łapiński, Agata Sulej, Jiandong Liu, Shamba S. Mondal, Michał Pawlak, Łukasz Bugajski, Katarzyna Piwocka, Thomas Brand, Peter Karl Kohl, Vladimir P. Korzh, Cecilia Lanny Winata

The paper profiles the transcriptome of the zebrafish atrioventricular canal to identify molecular signatures of pacemaker and valve mesenchyme, revealing conserved features with mammalian AV node and cardiac valves.

Cellular and Molecular Life Sciences · Sep 23, 2021Peer-reviewedDevelopmental Biology