Katarzyna Piwocka

This study identifies Polθ as a therapeutic target in DNMT3A-mutated leukemia by showing its essential role in DNA repair and replication fork restart, and demonstrates that its inhibition enhances standard therapies.

This study shows hypoxia alters myeloid cell functions in glioblastoma by changing gene expression and chromatin accessibility, affecting immune cell markers and transcription factor regulation.

The paper profiles the transcriptome of the zebrafish atrioventricular canal to identify molecular signatures of pacemaker and valve mesenchyme, revealing conserved features with mammalian AV node and cardiac valves.

The paper analyzes transcriptomic and chromatin accessibility changes in zebrafish cardiomyocytes during heart development to identify key regulatory networks and their disruption in mutant lines.

This study shows that tunneling nanotubes (TNTs) mediate stroma-mediated imatinib resistance in leukemic cells by transferring survival proteins.