Author

Purnima Kumar

University of OxfordORCID 0000-0001-5844-1341Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Angela J. RusselliD· 1 shared Carole J. R. BatailleiD· 1 shared Laia Josa‐CulleréiD· 1 shared Paresh VyasiD· 1 shared Thomas A. MilneiD· 1 shared Thomas JacksoniD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperPharmacology & Toxicology

Angela J. RussellORCID

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1 paper

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintJan 6, 2024

HDAC inhibitor derivatives induce differentiation of leukemic cells through two distinct and separable mechanisms

Purnima Kumar, Laia Josa‐Culleré, Thomas Jackson…·Angela J. Russell

The paper shows HDAC inhibitors induce AML cell differentiation via two distinct mechanisms: one through G1 arrest and another through G2 arrest via Aurora A and GSK3 inhibition.

1 citation

humanbulk RNA-seq

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