Richard B. Crouse

Acetylcholine signaling in the medial prefrontal cortex mediates the ability to learn an active avoidance response following learned helplessness training

This study investigates the role of acetylcholine signaling in the medial prefrontal cortex during learned helplessness training and active avoidance tasks, finding sex-specific effects on escape performance and potential contributions to depressive symptoms.

Basal forebrain cholinergic neurons are part of the threat memory engram

The paper identifies basal forebrain cholinergic neurons as essential partners in threat memory engrams, showing distinct activation patterns for learned and innate threats.

A novel mouse model of focal limbic seizures that reproduces behavioral impairment associated with cortical slow wave activity

This paper describes a novel mouse model of focal limbic seizures that correlates behavioral impairment with cortical slow wave activity, similar to human temporal lobe seizures.

Acetylcholine is released in the basolateral amygdala in response to predictors of reward and enhances learning of cue-reward contingency

The paper shows that acetylcholine in the basolateral amygdala increases during reward-related events and enhances learning of cue-reward associations in mice.