Giorgio Trinchieri

This study shows IL-17RC signaling in the intestine prevents atherosclerosis by controlling microbiota and perivascular innervation, with loss of IL-17RC increasing inflammation and disease.

The paper studies chaotic dynamics in hematopoiesis using mouse data, showing leukocyte fluctuations are chaotic and can transition to oscillations with B cell accumulation.

The paper introduces TkNA, a causal-inference framework for analyzing host-microbiota multi-omics data to identify master regulators of interactions.

The paper identifies betacellulin as a target of omega-3 fatty acids in reducing NASH by suppressing inflammation and fibrosis through mechanisms involving hepatic stellate cells and macrophages.

JAMS provides a framework for analyzing microbiological genomic data, enabling taxonomic and functional exploration of shotgun and 16S sequences with validated performance against MetaPhlAn 4.