Author

Manuel García‐Jaramillo

Oregon State UniversityORCID 0000-0003-2987-2913Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Amiran DzutseviD· 1 shared Andrey MorguniD· 1 shared Archana UnnikrishnaniD· 1 shared Arlan G RichardsoniD· 1 shared Austin J. Hammer· 1 shared Chloe L. FenderiD· 1 shared Christopher A. GaulkeiD· 1 shared Claudia S. MaieriD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperSystems Biology

Amiran DzutsevORCID

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3 papers

Recent·Most cited

Age, Sex, and mitochondrial-haplotype influence gut microbiome composition and metabolites in a genetically diverse rat model.

Hoang Van M. Nguyen, E Villamil Cabello, David W. Dyer, Chloe L. Fender, Manuel García‐Jaramillo, Norman G. Hord, Steven N. Austad, Arlan G Richardson, Archana Unnikrishnan

This study shows that sex and mitochondrial-haplotype influence age-related changes in gut microbiome composition and metabolites in rats.

Aging · Feb 27, 2025Peer-reviewedMicrobiology

Gut microbiota metabolically mediate intestinal helminth infection in Zebrafish

Austin J. Hammer, Christopher A. Gaulke, Manuel García‐Jaramillo, Connor Leong, Jeffrey T. Morré, Michael J. Sieler, Jan Frederik Stevens, Yuan Jiang, Claudia S. Maier, Michael L. Kent, Thomas J. Sharpton

This study identifies gut microbiota-mediated metabolites that influence intestinal helminth infection in zebrafish, highlighting potential therapeutic targets.

mSystems · Aug 27, 2024Peer-reviewedMicrobiology

Multi-omic network analysis identified betacellulin as a novel target of omega-3 fatty acid attenuation of western diet-induced nonalcoholic steatohepatitis.

Jyothi Padiadpu, Manuel García‐Jaramillo, Nolan K. Newman, Jacob W. Pederson, Richard Rosario Rodrigues, Zhipeng Li, S. P. Singh, Philip M. Monnier, Giorgio Trinchieri, Kevin Brown, Amiran Dzutsev, Natalia Shulzhenko, Donald Β. Jump, Andrey Morgun

The paper identifies betacellulin as a target of omega-3 fatty acids in reducing NASH by suppressing inflammation and fibrosis through mechanisms involving hepatic stellate cells and macrophages.

EMBO Molecular Medicine · Oct 20, 2023Peer-reviewedSystems Biology