A community-consensus reconstruction of Chinese Hamster metabolism enables structural systems biology analyses to decipher metabolic rewiring in lactate-free CHO cells
Pablo Di Giusto, Dong‐Hyuk Choi, Athanasios Antonakoudis…·Nathan E. Lewis
The paper presents iCHO3K, a comprehensive metabolic model of Chinese Hamster cells, and uses it to analyze metabolic changes in lactate-free cells, identifying structural insights into metabolic rewiring.