Author

Christelle En Lin Chua

National University of SingaporeORCID 0000-0001-5929-403XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Aditi GnanasekariD· 1 shared Andy Wing Chun PangiD· 1 shared Ann H. CapliniD· 1 shared Biswanath ChowdhuryiD· 1 shared Ceyda ÇoruhiD· 1 shared Daniel MuliaditaniD· 1 shared Feng YueiD· 1 shared Frank B. FurnariiD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperCancer Biology

Aditi GnanasekarORCID

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1 paper

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedFeb 10, 2025

Breakage fusion bridge cycles drive high oncogene copy number, but not intratumoral genetic heterogeneity or rapid cancer genome change

Siavash R. Dehkordi, Ivy Tsz-Lo Wong, Jing Ni…·Vineet Bafna

The paper introduces OM2BFB, an algorithm detecting BFB amplifications using OGMs, showing high precision and recall, and finds BFB events are common in certain cancers but not linked to intratumoral heterogeneity or rapid genome change.

30 citationstop 1%

humanwhole-genome sequencing

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