Author

Michael Dominic Sacco

Stanford MedicineORCID 0000-0001-5930-7363Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1

Frequent Co-Authors

Alexandros MakriyannisiD· 1 shared Brian K. ShoichetiD· 1 shared Cheng-Guo WuiD· 1 shared Christos Iliopoulos‐TsoutsouvasiD· 1 shared Dmytro S. RadchenkoiD· 1 shared Emma Santos· 1 shared Georgios SkiniotisiD· 1 shared Isabella GlenniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Alexandros MakriyannisORCID

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1 paper

Recent·Most cited

BiochemistryJournal of Medicinal ChemistryPeer-reviewedJul 3, 2026

Library docking for Cannabinoid-2 Receptor ligands

Moira M. Rachman, Christos Iliopoulos‐Tsoutsouvas, Michael Dominic Sacco…·Brian K. Shoichet

This study uses library docking to identify subtype-selective CB2 receptor ligands, finding improved hit rates and affinities with larger libraries and structure-based optimization.

DOI 10.1021/acs.jmedchem.6c00835

protein structuredeep learning

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