Library docking for Cannabinoid-2 Receptor ligands
Moira M. Rachman, Christos Iliopoulos‐Tsoutsouvas, Michael Dominic Sacco, Xinyu Xu, Cheng-Guo Wu, Emma Santos, Isabella Glenn, Lu Paris, Michelle K. Cahill, Suthakar Ganapathy, Tia A. Tummino, Yurii S. Moroz, Dmytro S. Radchenko, Meri Okorie, Vivianne L. Tawfik, , Brian K. Shoichet
This study uses library docking to identify subtype-selective CB2 receptor ligands, finding improved hit rates and affinities with larger libraries and structure-based optimization.
Journal of Medicinal Chemistry · Jul 3, 2026Peer-reviewedBiochemistry