Cell BiologybioRxivPreprint
A microscopy reporter for cGAMP reveals rare cGAS activation following DNA damage, and a lack of correlation with micronuclear cGAS enrichment
Vivianne Lebrec, Negar Afshar, Lauren R. Davies…·Christian Zierhut
The paper introduces a cGAMP reporter to visualize cGAS activation in response to DNA damage and finds that cGAS activation is limited to a subfraction of cells and not correlated with micronuclear cGAS enrichment.