Author

Christian Zierhut

Institute of Cancer ResearchORCID 0000-0003-3501-603XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Amit GroveriD· 1 shared Benjamin Peter FairfaxiD· 1 shared Bruno BeernaertiD· 1 shared Claire WillisiD· 1 shared David R. WithersiD· 1 shared Dmitry I. GabrilovichiD· 1 shared Eileen E. ParkesiD· 1 shared Eleni AdamopoulouiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperImmunology

Amit GroverORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJan 2, 2026

TMEM33 deletion potentiates anti-tumor CD8+ T cell immunity

Matthew P. Jackson, T. Zhao, Gusztav Milotay…·Eileen E. Parkes

This study shows TMEM33 limits progenitor-exhausted CD8+ T cells, enhances anti-tumor responses, and correlates with improved survival in melanoma patients.

DOI 10.64898/2026.01.01.697288

mousebulk RNA-seq

𝕏 PostBluesky

Cell BiologybioRxivPreprintMay 13, 2024

A microscopy reporter for cGAMP reveals rare cGAS activation following DNA damage, and a lack of correlation with micronuclear cGAS enrichment

Vivianne Lebrec, Negar Afshar, Lauren R. Davies…·Christian Zierhut

The paper introduces a cGAMP reporter to visualize cGAS activation in response to DNA damage and finds that cGAS activation is limited to a subfraction of cells and not correlated with micronuclear cGAS enrichment.

12 citations

humanimaging

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