Brian B. Haab

The circadian gene Dec2 promotes pancreatic cancer dormancy by regulating tumor cell antigen presentation to facilitate immune evasion

This study identifies Dec2 as a circadian gene that promotes pancreatic cancer dormancy by reducing MHC-I antigen presentation, enabling immune evasion.

Glucose-dependent glycosphingolipid biosynthesis fuels CD8+ T cell function and tumor control

This study identifies glucose-dependent glycosphingolipid biosynthesis as essential for CD8+ T cell expansion and tumor control, independent of energy production.

Multiplexed Glycan Immunofluorescence Identification of Pancreatic Cancer Cell Subpopulations in Both Tumor and Blood Samples

This study identifies PDAC cancer cell subpopulations using multiplexed glycan immunofluorescence and shows consistent aberrant glycan signatures in both tumor and blood samples, improving detection beyond CA19-9 alone.

Metabolomics and 13C Labelled Glucose Tracing to Identify Carbon Incorporation into Aberrant Cell Membrane Glycans in Cancer

This study uses metabolomics and 13C tracing to examine glucose allocation to membrane glycans in pancreatic cancer cell lines, revealing differences in glycan synthesis and metabolic pathways.

A Rigorous Multi-Laboratory Study of Known PDAC Biomarkers Identifies Increased Sensitivity and Specificity Over CA19-9 Alone

This study evaluates combinations of PDAC biomarkers across multiple labs, finding improved sensitivity and specificity for early-stage detection compared to CA19-9 alone.

CarboGrove: a resource of glycan-binding specificities through analyzed glycan-array datasets from all platforms

CarboGrove integrates and analyzes glycan-array data from multiple sources to provide insights into glycan-binding specificities and support experimental and computational research.