The heart-liver axis controls platelet turnover by hepatic STAT3 phosphorylation and TPO regulation after acute myocardial infarction
Friedrich Reusswig, Benjamin Tajdar, Simone Gorreßen…·Margitta Elvers
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Heinrich Heine University DüsseldorfORCID 0000-0001-5964-0385Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Friedrich Reusswig, Benjamin Tajdar, Simone Gorreßen…·Margitta Elvers
Lili Donner, Simone Gorreßen, Jens W. Fischer, Margitta Elvers
This study shows that Alzheimer's transgenic mice experience reduced left ventricular function after myocardial ischemia and reperfusion, linked to elevated IL-1 beta, altered platelet activation, and cardiac remodeling.
Kim Jürgen Krott, Friedrich Reusswig, Matthias A. Dille…·Margitta Elvers
This study shows that platelets induce cardiac cell apoptosis via FasL after acute myocardial infarction, contributing to cardiac damage and dysfunction.