Yu S. Huang

This study compares three CNA detection algorithms, showing that Accucopy performs best overall, while purity and sequencing depth significantly affect performance.

eGADA improves upon GADA by using a Red-Black tree, C++ code, Boost libraries, and Python API for faster and more efficient genomic segmentation.

The paper introduces the Sentieon ctDNA pipeline for accurate and efficient small somatic variant calling from ctDNA sequencing data, showing improved accuracy over existing methods.