Author

Ueli Nachbur

The University of MelbourneORCID 0000-0001-5968-2235Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

David KomanderiD· 2 shared Aleksandra Bankovacki· 1 shared Andrew Ian WebbiD· 1 shared Anthony CerraiD· 1 shared Che A. StaffordiD· 1 shared Cheree Fitzgibbon· 1 shared Jack A Alexandrovics· 1 shared James M. MurphyiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

David KomanderORCID

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2 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedJul 17, 2026

ZnF-UBP domains regulate deubiquitinase activity by relieving ubiquitin product inhibition

Jack A Alexandrovics, Rashmi Agrata, Jan André Hane…·David Komander

The paper investigates ZnF-UBP domains in USP DUBs, showing they relieve product inhibition by facilitating Ub release, thereby regulating enzyme activity.

1 citation

humanproteomics

𝕏 PostBluesky

Molecular BiologybioRxivPreprintMay 1, 2021

Oligomerization-driven MLKL ubiquitylation antagonises necroptosis

Zikou Liu, Laura F. Dagley, Kristy Shield‐Artin…·John Silke

This study demonstrates that MLKL ubiquitylation, triggered by oligomerization, regulates necroptosis by modulating MLKL activity and turnover.

3 citations

mousehuman

𝕏 PostBluesky