Romain Perbet

The paper identifies distinct proteomic signatures in brain-derived extracellular vesicles from 3R and 4R tauopathies, linking them to disease-specific cellular and molecular changes.

The paper investigates SARS-CoV-2 infection in the hypothalamus and associated regions, showing viral entry receptors and susceptibility factors linked to neurological symptoms in COVID-19.

The paper compares the bioactivity of fibrillar and oligomeric tau forms in Alzheimer's disease, finding HMW tau more potent in glial activation and tau propagation.

This study shows that tau-containing extracellular vesicles from neurons transfer tau to astrocytes, disrupting their mitochondrial function, with 3R tau being more damaging than 4R tau.