Author

Élodie Leroux

InsermORCID 0000-0002-1216-4243Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Jeanne EspourteilleiD· 2 shared Kevin RichetiniD· 2 shared Luc BuéeiD· 2 shared Morvane ColiniD· 2 shared Nicolas ToniiD· 2 shared Romain PerbetiD· 2 shared Valentin ZuffereyiD· 2 shared Aatmika BarveiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersNeuroscience

Jeanne EspourteilleORCID

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2 papers

Recent·Most cited

Astrocyte and mitochondrial footprints in brain-derived extracellular vesicles predict tau pathology

Jeanne Espourteille, Aatmika Barve, Valentin Zufferey, Élodie Leroux, Romain Perbet, Séverine Bagard, Raphaëlle Caillierez, Claude‐Alain Maurage, Nicolas Toni, Luc Buée, Morvane Colin, Kevin Richetin

The paper identifies distinct proteomic signatures in brain-derived extracellular vesicles from 3R and 4R tauopathies, linking them to disease-specific cellular and molecular changes.

bioRxiv · Jan 9, 2025 · PreprintNeuroscience

Accumulation of Tau in Extracellular Vesicles Disturbs the Astrocytic Mitochondrial System

Romain Perbet, Valentin Zufferey, Élodie Leroux, Enea Parietti, Jeanne Espourteille, Lucas Culebras, Sylvain Perriot, Renaud Du Pasquier, Séverine Bégard, Vincent Deramecourt, Nicole Déglon, Nicolas Toni, Luc Buée, Morvane Colin, Kevin Richetin

This study shows that tau-containing extracellular vesicles from neurons transfer tau to astrocytes, disrupting their mitochondrial function, with 3R tau being more damaging than 4R tau.

bioRxiv · Feb 15, 2023 · PreprintNeuroscience