Olga I. Lavrik

The paper shows that nucleosomes enhance DNA polymerase β activity in linker DNA and that PARP1/PARP2 regulate this activity and BER sub-pathway choice.

The paper investigates the mechanism of long patch base excision repair by analyzing how FEN1 and Polβ interact through equilibrium nucleotide areas rather than a gap-translation mechanism.

This study investigates how HPF1 modulates PARP1 and PARP2 activity to influence FUS-dependent compartment formation during DNA damage.

The paper investigates ADP-ribosylation of human ribosomal proteins by PARP1 and PARP2, showing that 60S subunit RPs are more modified and HPF1 enhances this modification, while core histones compete with RPs for PARylation.

This study investigates how structural features of damaged nucleosomes influence PARP1 and PARP2 activities in histone ADP-ribosylation during genotoxic stress.