Author

Loïc Hamon

InsermORCID 0000-0003-2032-7994Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2

Frequent Co-Authors

David PastréiD· 2 shared Anastasia S. Singatulina· 1 shared Bénédicte Desforges· 1 shared Clément Demongin· 1 shared Léa CeschiiD· 1 shared Maria V. SukhanovaiD· 1 shared Mikhail M. KutuzoviD· 1 shared Olga I. LavrikiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

David PastréORCID

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2 papers

Recent·Most cited

Molecular BiologyNucleic Acids ResearchPeer-reviewedFeb 19, 2026

HPF1 REGULATES THE FORMATION OF FUS-DEPENDENT COMPARTMENTS BY PARP1 AND PARP2 ACTIVATION ON DAMAGED DNA

Anastasia S. Singatulina, Maria V. Sukhanova, Loïc Hamon…·Olga I. Lavrik

This study investigates how HPF1 modulates PARP1 and PARP2 activity to influence FUS-dependent compartment formation during DNA damage.

DOI 10.1093/nar/gkag183

experimental assay

𝕏 PostBluesky

Molecular BiologybioRxivPreprintJul 25, 2023

RNA and FUS act in concert to prevent TDP-43 spatial segregation

Clément Demongin, S. Tranier, Vandana Joshi…·Loïc Hamon

The paper shows that FUS and TDP-43 interact in mRNA-rich compartments, with FUS enabling TDP-43 to mix and prevent aggregation, and that this interaction is disrupted by pathological mutations.

DOI 10.1101/2023.07.25.550456

experimental assay

𝕏 PostBluesky