Author

Devi Santhosh

University of Wisconsin–MadisonORCID 0000-0001-5998-6351Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Neuroscience· 2 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Hyo Jun Kwon· 2 shared Zhen HuangiD· 2 shared Aakrosh RataniD· 1 shared Aju Antony· 1 shared Boney KuriakoseiD· 1 shared Chao CheniD· 1 shared Deepak Tanneeru· 1 shared Derek Vargas· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Hyo Jun Kwon

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

NeuroscienceeLifePeer-reviewedDec 5, 2024

A novel monomeric amyloid β-activated signaling pathway regulates brain development via inhibition of microglia

Hyo Jun Kwon, Devi Santhosh, Zhen Huang

This study identifies a novel monomeric Aβ-activated signaling pathway in microglia that regulates brain development by inhibiting microglial immune activation and preventing neuronal ectopia.

1 citation

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintJul 24, 2023

Monomeric amyloid-β inhibits microglial inflammatory activity in the brain via an APP/heterotrimeric G protein-mediated pathway

Hyo Jun Kwon, Devi Santhosh, Zhen Huang

This study identifies an APP/heterotrimeric G protein-mediated pathway that suppresses microglial inflammation via Aβ monomers, revealing a novel regulatory mechanism in brain development and Alzheimer's disease.

DOI 10.1101/2023.07.24.550398

mouseexperimental assay

𝕏 PostBluesky

GeneticsCommunications BiologyPeer-reviewedApr 12, 2021

Human ACE2 receptor polymorphisms predict SARS-CoV-2 susceptibility

Kushal Suryamohan, Devan C. Diwanji, Eric W. Stawiski…·Somasekar Seshagiri

This study identifies ACE2 receptor polymorphisms that may influence susceptibility to SARS-CoV-2 by altering the interaction between ACE2 and the viral S-protein.

299 citationstop 1%

humanwhole-genome sequencing

𝕏 PostBluesky