Sentinel cells enable genetic detection of SARS-CoV-2 Spike protein
Zara Y. Weinberg, Claire E. Hilburger, Matthew J. Kim, Longxing Cao, Mir Mubashir Khalid, Sarah Elmes, Devan C. Diwanji, Evelyn Hernandez, Jocelyne Lopez, Kaitlin Schaefer, Amber M. Smith, Fengbo Zhou, G. Renuka Kumar, Mélanie Ott, David A. Baker, Hana El‐Samad
This paper introduces SARSNotch, a sentinel cell system that detects SARS-CoV-2 Spike protein and triggers genetic responses in cell lines and T lymphocytes.
bioRxiv · Apr 20, 2021 · PreprintSynthetic Biology