Alexander Lang

This study shows that anemia in coronary artery disease patients increases release of red blood cell-derived extracellular vesicles (REVs) that promote endothelial dysfunction by enhancing nitric oxide consumption and oxidative stress.

The paper compares fluorescence staining methods to classical histochemical techniques for determining infarct and scar size in murine reperfused myocardial infarction models.

The paper uses long-read mRNA sequencing to analyze PGC-1α transcripts in murine and human hearts, identifying novel isoforms and promoters regulated in ischemia and obesity.