Author

Daniel Oehler

Düsseldorf University HospitalORCID 0000-0002-0435-4119Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:long-read sequencing· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Agnieszka Rybak‐WolfiD· 1 shared Alessandro PrigioneiD· 1 shared Alexander LangiD· 1 shared Amin PolziniD· 1 shared André SpychalaiD· 1 shared Annett BöddrichiD· 1 shared Axel GödeckeiD· 1 shared Barbara MlodyiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Agnieszka Rybak‐WolfORCID

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2 papers

Recent·Most cited

Mutant Huntingtin impairs neurodevelopment in human brain organoids through CHCHD2-mediated neurometabolic failure

Paweł Lisowski, Selene Lickfett, Agnieszka Rybak‐Wolf, Carmen Menacho, Stephanie Le, Tancredi Massimo Pentimalli, Sofia Notopoulou, Werner Dykstra, Daniel Oehler, Sandra López-Calcerrada, Barbara Mlody, Maximilian Otto, Haijia Wu, Yasmin Richter, Philipp Roth, , Alessandro Prigione

This study shows that mutant Huntingtin causes neurodevelopmental issues in human brain organoids by disrupting CHCHD2, leading to mitochondrial and metabolic problems.

Nature Communications · Aug 22, 2024Peer-reviewedNeuroscience

Full-length transcriptomic analysis in murine and human heart reveals diversity of PGC-1α promoters and isoforms regulated distinctly in myocardial ischemia and obesity

Daniel Oehler, André Spychala, Axel Gödecke, Alexander Lang, Norbert Gerdes, Jorge Lira Ruas, Malte Kelm, Julia Szendroedi, Ralf Westenfeld

The paper uses long-read mRNA sequencing to analyze PGC-1α transcripts in murine and human hearts, identifying novel isoforms and promoters regulated in ischemia and obesity.

BMC Biology · Jul 30, 2022Peer-reviewedGenetics