Odvogmed Bayansan

This study identifies a mutation in the vesicular acetylcholine transporter (UNC-17) that increases tubulin acetylation, impairing axonal transport by disrupting interactions between UNC-104, UNC-17, and MEC-17.

This study shows that tubulin glutamylation and tyrosination crosstalk regulates kinesin-3 motor function and axonal transport in C. elegans neurons.

The paper shows UNC-10/SYD-2 links kinesin-3 to RAB-3-containing vesicles without the motor's PH domain, enhancing transport and strengthening weak motor-lipid interactions.