Author

Dongsheng Han

Vanderbilt UniversityORCID 0000-0001-6008-4013Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:Drosophila· 1 Approach:experimental assay· 1 Assay:long-read sequencing· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Jared T. NordmaniD· 2 shared Mary Lauren BentoniD· 2 shared Cole ShepherdiD· 1 shared Jonathan P. DaviesiD· 1 shared Lars PlateiD· 1 shared Samantha H. SchaffneriD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 12 mutual co-author links

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2 shared papersMolecular Biology

Jared T. NordmanORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintSep 26, 2025

Nanopore-based sequencing of active DNA replication reveals key principles of metazoan replication fork progression, origin and termination sites

Dongsheng Han, Cole Shepherd, Mary Lauren Benton, Jared T. Nordman

The paper uses nanopore sequencing and DNAscent to measure replication fork progression and origin/termination sites in Drosophila, revealing non-uniform fork speeds and variable origin positions.

1 citation

Drosophilalong-read sequencing

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Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewedSep 18, 2023

BRWD3 promotes KDM5 degradation to maintain H3K4 methylation levels

Dongsheng Han, Samantha H. Schaffner, Jonathan P. Davies…·Jared T. Nordman

This study shows BRWD3 promotes KDM5 degradation, which maintains H3K4 methylation levels by balancing H3K4me1 and H3K4me3.

12 citations

statistical model

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