Issam El Naqa

This study shows that higher ploidy reduces gemcitabine potency and delays cell death by altering drug exposure kinetics and response timing.

The paper introduces CLONEID, a framework for organizing clone-resolved data to enable longitudinal genotype-to-phenotype mapping in experiments with repeated molecular and phenotypic measurements.

The paper integrates sequencing and imaging data to map cell cycle states, linking transcriptome states to living cells with high resolution.