Author

Debbie L. C. van den Berg

Erasmus MCORCID 0000-0001-6026-8808Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Anne L. Kuijpers-Korporaal· 1 shared Danny HuylebroeckiD· 1 shared Franç Guillemot· 1 shared Hedda B. SomseniD· 1 shared K. Peter Kats· 1 shared Koji OishiiD· 1 shared Kristel N. EigenhuisiD· 1 shared Maarten W.J. FornerodiD· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperDevelopmental Biology

Anne L. Kuijpers-Korporaal

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2 papers

Recent·Most cited

Developmental BiologybioRxivPreprintNov 26, 2024

The Integrator complex prevents premature neuronal differentiation through global control of transcription elongation.

Hedda B. Somsen, Kristel N. Eigenhuis, Anne L. Kuijpers-Korporaal…·Debbie L.C. van den Berg

The paper shows that the Integrator complex regulates neuronal differentiation by controlling RNA polymerase II pause-release, and that disrupting this process leads to premature neuronal gene expression and developmental defects.

DOI 10.1101/2024.11.26.625369

humanbulk RNA-seq

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NeurosciencebioRxivPreprintOct 1, 2018

Temporal control of cortico-thalamic neuron specification by regulation of Neurogenin activity and Polycomb repressive complexes

Koji Oishi, Debbie L. C. van den Berg, Franç Guillemot

The paper shows that Neurog1/2 regulate the specification of cortico-thalamic neurons through Fezf2 and Foxp2, and that their activity and epigenetic repression control the temporal production of this neuron subtype.

4 citations

mousebulk RNA-seq

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