Author

Kristel N. Eigenhuis

Erasmus MCORCID 0000-0002-8816-5808Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

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Anne L. Kuijpers-Korporaal· 1 shared Danny HuylebroeckiD· 1 shared Debbie L.C. van den BergiD· 1 shared Hedda B. SomseniD· 1 shared K. Peter Kats· 1 shared Maarten W.J. FornerodiD· 1 shared Mariana Pelicano de AlmeidaiD· 1 shared Mike R. DekkeriD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperDevelopmental Biology

Anne L. Kuijpers-Korporaal

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1 paper

Recent·Most cited

Developmental BiologybioRxivPreprintNov 26, 2024

The Integrator complex prevents premature neuronal differentiation through global control of transcription elongation.

Hedda B. Somsen, Kristel N. Eigenhuis, Anne L. Kuijpers-Korporaal…·Debbie L.C. van den Berg

The paper shows that the Integrator complex regulates neuronal differentiation by controlling RNA polymerase II pause-release, and that disrupting this process leads to premature neuronal gene expression and developmental defects.

DOI 10.1101/2024.11.26.625369

humanbulk RNA-seq

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