Author

Gang Ye

University of MinnesotaORCID 0000-0001-6034-2174Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Gang Ye1 paper · Hospital for Sick Children

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:structural biology· 1

Frequent Co-Authors

Bo Gao· 1 shared Chao WangiD· 1 shared Charles C. BaileyiD· 1 shared Claire E. KitzmilleriD· 1 shared Claudia Ruiz Bayona· 1 shared David Kyle MeyerholziD· 1 shared Divyasha SaxenaiD· 1 shared Fan BuiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Bo Gao

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1 paper

Recent·Most cited

MicrobiologyNature CommunicationsPeer-reviewedOct 27, 2026

A SARS-CoV-2 entry inhibitor trimerizes to lock the spike protein in a closed conformation

Huihui Mou, Bo Gao, Gang Ye…·Hyeryun Choe

This paper describes a trimeric inhibitor, S22, that stabilizes the SARS-CoV-2 spike protein in a closed conformation, preventing ACE2 binding and viral entry.

DOI 10.1038/s41467-026-78835-9

humanstructural biology

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