Maxime Assous

This study shows that nicotinic acetylcholine receptors in midbrain neurons control dopamine release in the striatum, affecting reward learning and action selection in mice.

The paper identifies a long-range inhibitory mechanism in striatal circuits that links synchronized cholinergic activity to pause generation during reinforcement learning.

This study investigates how Parkinson's disease disrupts cholinergic interneuron control of GABAergic circuits in the striatum, showing reduced nicotinic AChR expression in interneurons in disease models.

The paper investigates cholinergic control of striatal GABAergic microcircuits by showing CINs activate multiple GIN populations through mAChRs and nAChRs.

This study shows that Nrp2 signaling is essential for corticostriatal synaptic maintenance, spine structure, and learning in mice, with implications for neurodevelopmental disorders.