Comparative profiling of carnitine palmitoyltransferase 1 isoforms reveals vincamine as a selective carnitine palmitoyltransferase 1b inhibitor
Anthony Wong, William Luo, Justin Xuan…·Zhan Chen
This study identifies vincamine as a selective CPT1b inhibitor using a high-throughput assay, expanding the known isoform profile of chlorpromazine and demonstrating the feasibility of selective CPT1 isoform modulation.