Juan Carlos Zúñiga‐Pflücker

The paper shows HEB and TCR signaling work together to increase Id3, which is needed for fetal γδ T cells to mature into IL-17-producing cells.

This study identifies two mouse thymic macrophage populations and shows their role in T cell development, particularly highlighting the requirement for Csf1r-expressing myeloid cells during the DN3-to-DN4 transition.

This study shows that Id3 deficiency affects the development of gamma delta T cell subsets by regulating the generation and function of the Vgamma1Vdelta6.3 TCR.

This study shows Notch1 signaling is essential for specifying and expanding the medullary thymic epithelial cell (mTEC) progenitor pool during mouse fetal development.

The paper describes the generation of genetically annotated iPSC lines from healthy donors and demonstrates their use in creating disease-relevant cell types and identifying variant-preferred lines for control in disease modeling.