Yubing Han

This paper introduces DeepIso, a self-supervised framework that enhances isotropic resolution in 3D fluorescence microscopy by restoring axial frequency content without requiring explicit PSF models or system calibration.

The paper identifies a direct, MFRN-independent Fe(II) transfer pathway at mitochondria-lysosome contacts, bypassing the cytosolic labile iron pool.

I2SIM improves axial resolution in 3D-SIM by using interference and spectral optimization, achieving 130 nm resolution for subcellular structures.

This paper introduces VISPR, a method for accurate 3D PSF retrieval in SMLM, enabling precise localization and aberration assessment.