Sudharshan Ravi

DeltaFBA predicts metabolic flux changes between conditions using genome-scale models and gene expression data without requiring a specified cellular objective.

This study identifies nutrient signaling pathways that regulate amyloid clearance and synaptic loss in Alzheimer's disease, showing both protective and harmful effects.

This study identifies metabolic dysfunction, particularly in the TCA cycle, as an early and causative event in Alzheimer's disease using a transgenic C. elegans model.