A combination of the geroprotectors trametinib and rapamycin is more effective than either drug alone
Lisonia Gkioni, Tobias Nespital, Maarouf Baghdadi, Carolina Monzó, Jitin Bali, Taim Nassr, Anna Lena Cremer, Andreas Beyer, Joris Deelen, Heiko Backes, Sebastian Grönke, Linda Partridge
This study shows that combining trametinib and rapamycin extends mouse lifespan more than either drug alone and improves health markers in older age.
Nature Aging · May 28, 2025Peer-reviewedPhysiology