Tobias Jumel

This study shows that disrupting plasma membrane lipid asymmetry in mammalian cells alters cellular energetics by shifting metabolism from anabolic to catabolic states.

The paper quantifies stop codon miscoding in E. coli under stress, showing up to 80% error rates and environmental regulation of protein heterogeneity.

This study shows that hepatocyte differentiation requires anisotropic expansion of bile canaliculi, with loss of polarity leading to cholangiocyte-like gene expression.