Cell BiologyAdvanced SciencePeer-reviewed
Sonoepigenetic Modification Mechanoprimes Early Osteogenic Commitment in Mesenchymal Stem Cells
Lizebona August Ambattu, Blanca del Rosal, Carmelo Ferrai, Leslie Y. Yeo
This study shows that high-frequency nanomechanostimulation induces chromatin fluctuations in mesenchymal stem cells through Ca2+ and cAMP crosstalk, promoting osteogenic commitment without osteogenic factors.