Carmelo Ferrai

This study shows that variant U1 snRNAs affect gene expression and cell cycle in human iPS cells through alternative splicing changes.

This study shows that nanotopography regulates pluripotency in mESCs by altering chromatin state through the mechanosensitive demethylase KDM3A.

This study shows that high-frequency nanomechanostimulation induces chromatin fluctuations in mesenchymal stem cells through Ca2+ and cAMP crosstalk, promoting osteogenic commitment without osteogenic factors.

The paper compares super-enhancer networks in embryonic stem cells and dopaminergic neurons, revealing their structural differences and functional roles in transcriptional regulation.

The paper shows that Pol II transcriptional clusters undergo a conserved condensation-dispersal sequence during stem cell differentiation across species.