Séverine Zirah

The paper identifies TFX as an antibiotic that inhibits arginyl-tRNA synthetase by acting as a Trojan-horse molecule, revealing it belongs to a broader family of natural inhibitors targeting various tRNA synthetases.

The paper identifies and characterizes the diversity of substrates and partner proteins for multinuclear non-heme iron-dependent oxidative (MNIO) enzymes, revealing new insights into their role in bacterial copper homeostasis and potential broader stress responses.

This paper identifies bufferins, a widespread family of ribosomal peptide metallophores that help bacteria adapt to copper stress by sequestering excess copper ions.