Simon Heß

The paper shows that alternative splicing of β2-subunits stabilizes Cav2.3 Ca2+ channel activity in midbrain dopamine neurons, contributing to their vulnerability in Parkinson's disease.

This paper combines perforated patch-clamp recordings with the added buffer approach to accurately quantify neuronal Ca2+ handling properties, including both immobile and mobile buffers.

The paper introduces a simpler method to estimate standard errors for ratiometric calcium estimators by using uncertainty propagation and Monte-Carlo methods, avoiding complex protocols and background models.