Lars Paeger

The paper identifies axonal branch points of parvalbumin interneurons as focal sites of Tau-induced degeneration in both mouse and human tauopathy.

This paper develops a 3D cortical brain tissue model with mature microglia that recapitulates Alzheimer's disease hallmarks and enables study of microglia phenotypes.

This study shows that neuronal and oligodendroglial tau, but not astroglial tau, contribute to tau-PET signals in 4-repeat tauopathies.

This paper combines perforated patch-clamp recordings with the added buffer approach to accurately quantify neuronal Ca2+ handling properties, including both immobile and mobile buffers.

This study shows that CAP2 regulates neuronal actin dynamics, spine density, and dendritic complexity in mice by interacting with cofilin and affecting its phosphorylation.