Author

Daniela Cunha‐Garcia

University of MinhoORCID 0000-0001-6090-3517Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Andreia Teixeira‐CastroiD· 3 shared Bruna Ferreira-LombaiD· 3 shared Daniela Monteiro‐FernandesiD· 3 shared Patrı́cia MacieliD· 3 shared Sara Duarte‐SilvaiD· 3 shared Sara R. GuerreiroiD· 3 shared Adrian Newman‐TancrediiD· 2 shared André Vidinha‐MiraiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Andreia Teixeira‐CastroORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintJan 24, 2026

Understanding corticosterone fluctuations and HPA-axis regulation in a mouse model of Spinocerebellar ataxia type 3

Joana Sofia Correia, Daniela Monteiro‐Fernandes, Sara R. Guerreiro…·Sara Duarte‐Silva

This study examines HPA-axis regulation and corticosterone fluctuations in SCA3 mice, finding normal HPA-axis function and minimal stress impact on disease progression.

DOI 10.64898/2026.01.22.701070

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintSep 4, 2025

The 5-HT1A receptor agonist NLX-112 rescues motor swimming deficits in Spinocerebellar Ataxia type 3 mice

Daniela Cunha‐Garcia, Bruna Ferreira-Lomba, Sara R. Guerreiro…·Adrian Newman‐Tancredi

This study tests the 5-HT1A agonist NLX-112 in SCA3 mice, finding it improves motor performance in a swimming test.

DOI 10.1101/2025.09.04.674027

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintAug 21, 2025

Efficacy of chronic 5-HT1A receptor agonism by NLX-112 in a mouse model of Spinocerebellar Ataxia type 3

Bruna Ferreira-Lomba, Sara R. Guerreiro, Sara Duarte‐Silva…·Patrı́cia Maciel

This study evaluates NLX-112, a 5-HT1A receptor agonist, in a mouse model of SCA3, showing improved motor function and neuroprotection when administered pre-symptomatically.

1 citation

mouseexperimental assay

𝕏 PostBluesky