Cell BiologybioRxivPreprint
C. elegans huntingtin, htt-1, promotes robust autophagy induction and survival under stress conditions
Christine Hyein Chung, Hanee Lee, Kyumin Park…·Junho Lee
This paper shows that C. elegans htt-1 promotes survival under stress by inducing autophagy, with wild-type human HTT rescuing survival defects and mutant HTT worsening them.
DOI 10.1101/2024.12.01.625591