Junho Lee

The paper analyzes genome-wide variation in Oscheius tipulae and finds three deeply divergent lineages structured by latitude rather than geography.

This study shows that dauer-specific gap junction rewiring in C. elegans shortens avoidance duration while preserving initiation, revealing how circuit reorganization balances flexibility and stability under stress.

The paper investigates how telomere repeats evolved in nematodes despite the specificity of telomere-binding proteins, finding that protein conservation and binding affinity correlate with the emergence of novel telomeric motifs.

This paper shows that C. elegans htt-1 promotes survival under stress by inducing autophagy, with wild-type human HTT rescuing survival defects and mutant HTT worsening them.

The paper studies mitochondrial structural diversity in C. elegans neuromuscular system across development using 3D electron microscopy and deep learning, finding correlations between mitochondrial properties and synaptic connections, and identifying stage-specific mitochondrial features in dauer.

This study shows that the Hippo pathway maintains neuronal structure by controlling microtubule stability in C. elegans, with implications for delaying neurodegeneration.

This study identifies daf-42 as an essential gene for dauer development in C. elegans, showing it is evolutionarily young and critical for survival under adverse conditions.

The paper identifies an X chromosome QTL associated with non-Mendelian inheritance and nullo-spermatid elimination in A. freiburgense.

The paper reconstructs the dauer connectome of nematodes to show how structural and connectivity changes in neurons lead to specific behaviors during developmental plasticity.

This study identifies dach-1, a cytochrome P450 gene, as a regulator of synaptic and developmental plasticity in C. elegans during the dauer stage, revealing its role in stress resistance and aldicarb sensitivity.

The paper identifies newly born genes in C. elegans using presence-absence variant genes and long-read sequencing, finding some have alternative alleles with evolutionary signatures.

The paper measures brood size and male-production rate in 96 C. elegans wild strains across reproductive periods, finding they are not genetically correlated and identifying loci associated with male-production rate.

The paper identifies a regulatory module in C. elegans IL2 neurons that specifies ciliary identity and behavior through DAF-19M, with conserved roles in nictation and mating.

The paper identifies QTL associated with benzimidazole resistance in nematodes using genetic mapping and phenotyping.