Radhika R. Gudi

This study shows CPAP stabilizes VPS4B protein and its localization to early endosomes, independent of its ESCRT-0 function, and reveals interactions critical for these processes.

This study shows that gut microbiota influences lupus-like disease outcomes differently in male and female NZM2328 mice, with females showing higher NET and complement pathway activation leading to disease susceptibility.

This paper identifies CPAP as a novel regulator of ESCRT pathway function during endosome maturation, showing its role in Rab5-to-Rab7 conversion and TSG101 recruitment to early endosomes.

This study shows that early-life colonization by Bacteroides fragilis in NOD mice accelerates type 1 diabetes progression by altering microbiota composition and immune responses.