Author

Niek van Wietmarschen

National Institutes of HealthORCID 0000-0001-6136-5757Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:whole-genome sequencing· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Raphael PavaniiD· 2 shared Wei WuiD· 2 shared William J. NathaniD· 2 shared André NussenzweigiD· 1 shared André NussenzweigiD· 1 shared Andrés Canela· 1 shared Aseem Z. AnsariiD· 1 shared Ashraf MohammediD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMolecular Biology

Raphael PavaniORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJan 19, 2022

Linking Dynamic DNA Secondary Structures to Genome Instability

Gabriel E. Matos-Rodrigues, Niek van Wietmarschen, Wei Wu…·André Nussenzweig

The paper identifies dynamic DNA secondary structures in vivo that contribute to genome instability by analyzing ssDNA converted to DSBs using S1-END-seq.

3 citations

humanDNA methylation

𝕏 PostBluesky

NeuroscienceNaturePeer-reviewedMar 25, 2021

Neuronal Enhancers are Hotspots For DNA Single-Strand Break Repair

Wei Wu, Sarah E. Kargbo-Hill, William J. Nathan…·André Nussenzweig

The paper identifies DNA single-strand breaks (SSBs) accumulating at neuronal enhancers and shows their repair involves PARP1, XRCC1, and DNA polymerase β.

223 citationstop 1%

humanDNA methylation

𝕏 PostBluesky